TRẦN QUỲNH HOA

Tiến sĩ chuyên ngành: Y Sinh

Email: hoatq@hufi.edu.vn

Khoa Sinh học và Môi trường

Trường ĐH Công Nghiêp Thực Phẩm TP.HCM

B104, 140 Lê Trọng Tấn, P. Tây Thạnh, Q.Tân Phú, TP.HCM

https://scholar.google.com/citations?user=QgH_HdUAAAAJ&hl=en&oi=ao

https://www.researchgate.net/profile/Quynh-Hoa-Tran

KINH NGHIỆM GIẢNG DẠY

Thâm niên giảng dạy: 16 năm (2006 -2021)

Môn học giảng dạy:

Sinh học phân tử, Kỹ thuật di truyền, Ứng dụng sinh học phân tử trong chẩn đoán, Miễn dịch học, Vi sinh vật y học, Dược liệu, Hóa sinh học, công nghệ Protein - Enzyme…

LĨNH VỰC NGHIÊN CỨU

Công nghệ sinh học, Y sinh dược

KINH NGHIỆM CHUYÊN MÔN

-        Chỉ thị phân tử chẩn đoán ung thư, bệnh di truyền, bệnh truyển nhiễm.

-        Cơ chế tác động của thuốc và các hoạt chất sinh học lên tế bào.

-        Công nghệ DNA tái tổ hợp, Protein tái tổ hợp.

-        Nghiên cứu và Sản xuất chế phẩm sinh học

ĐỀ TÀI – DỰ ÁN

CÔNG BỐ KHOA HỌC

PUBLICATIONS

1.     Quynh Hoa Tran, Dang Hieu Hoang, Minhyeok Song, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha. Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells. Exp Mol Med. 2021 Sep;53(9):1413-1422.

2.     Quynh Hoa Tran, Van Thai Than, Phuc Loi Luu, Declan Clarke, Hanh Ngoc Lam, Thanh-Giang Tan Nguyen, Dinh-Truong Nguyen, Phan Q. Duy, Dung Phung, Minh Nam Nguyen. A novel signature predicts recurrence risk and therapeutic response in breast cancer patients. Int J Cancer. 2021 Jun;148(11):2848-2856.

3.     Nguyen Van Gio, Tran Cong Manh, Nguyen Van Lam, Tran Quynh Hoa, Nguyen Minh Nam. Up-regulation of SET nuclear protooncogene is associated with early recurrence and poorer prognosis of hepatocellular carcinoma. Sci. Tech. Dev. J. - Health Sci. 2021;2(1):110-121.

4.     Quynh Hoa Tran, Van Gio Nguyen, Cong Manh Tran, Minh Nam Nguyen.  Down-regulation of solute carrier family 10 member 1 is associated with early recurrence and poorer prognosis of hepatocellular carcinoma. Heliyon. 2021 Mar;7(3):e06463.

5.     Tran Quynh Hoa, Vo Van Toi, Nguyen Minh Nam. High expression of DIMT1 correlates with poor prognosis and high risk of bone metastasis in breast cancer patients. Sci. Tech. Dev. J. - Health Sci. 2020;1(2):52-63.

6.     Goowon Yang, Minhyeok Song, Dang Hieu Hoang, Quynh Hoa Tran, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha. Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage. Exp Mol Med. 2020 Dec;52(12):2055-2068.

7.     Minhyeok Song, Goowon Yang, Tran Quynh Hoa, Hoang Dang Hieu, Ain Syafia Mohd Amin, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha. Anti-obesity effect of fermented persimmon extracts via activation of AMP-activated protein kinase. Biol Pharm Bull. 2020;43(3):440-449.

8.     Tran Quynh Hoa, Nguyen Dinh Quan, Nguyen Minh Nam. Roles of thiazolidinediones in type 2 diabetes mellitus treatment and weight gain. Journal of Science Technology and Food. 2020;20(3):11-18. (mini-review).

9.     Nguyen Van Gio, Tran Cong Manh, Tran Quynh Hoa, Hoang Xuan The, Nguyen Thi Thu Huyen, Lai Dinh Bien, Nguyen Minh Nam. SLC22A7 gene, a potential biomarker for the diagnosis and prognosis of hepatocellular carcinoma. Journal of Science Technology and Food. 2020;20(3):103-115.

10. In-Ja Park, Quynh Hoa Tran, Ain Syafia Mohd Amin, Thanh Lan Chu, Goowon Yang, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha. Transient activation of AMP-activated protein kinase at G1/S phase transition is required for control of S phase in NIH3T3 cells. Biochem Biophys Res Commun. 2018 Oct 2;504(2):367-373. (co-first author).

11. Jihyun Lee,  Goowon Yang, Young-Joo Kim, Quynh Hoa Tran, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha. Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway. Biochem Biophys Res Commun. 2017 Sep 23;491(3):733-739.

12. Hoang Tuan Anh, Nguyen Thi Hong Hanh, Le Bang Son, Nguyen Thi Thanh Loi, Nguyen Thi Nguyet, Tran Quynh Hoa, Dang Duc Trach. Analyzing the 5’ end of the cagA gene of three Helicobacter pylori quasi-species isolated from biopsies of one Vietnamese patient. Journal of Biology. 2002 Sep;24(3):53- 58.

13. Tran Cong Tuoc, Tran Quynh Hoa, Nguyen Thi Hong Hanh, Nguyen Van Phung, Bui Phuong Thuan. The presence of Helicobacter pylori type I (cagA⁺ status) in the gastric biopsies of Vietnamese patients. Journal of Biology. 2001 Jun;23(2):51-54.

14. Accession numbers of DNA sequences:
Sequences of cagA gene of Helicobacter pylori: AY176129, AJ313504, AJ313505.
Sequence of HP1125 gene of Helicobacter pylori: AF534874.

Conferences and Abstracts

1. Hoa Quynh Tran, Huyen Ngoc Vu, Xuan The Hoang, Van Thai Than, Kim Van Thi Le, Dinh-Truong Nguyen, Minh Nam Nguyen. Dehydrogenase/reductase 1 expression enhances survival of patients with hepatocellular carcinoma. Gut and Liver. 2018 Nov;12(6):105, P-LV-016. KDDW 2108 conference.

2.     Dinh-Truong Nguyen, Quynh Hoa Tran, Xuan The Hoang, Ngoc Huyen Vu, Kim Van Thi Le, Van Thai Than, Minh Nam Nguyen. Glyoxalase 2 correlates with redox signaling and enhances survival outcome in patients with hepatocellular carcinoma. Free Radical Biology and Medicine. 2018;128:S71. SfRBM's 25^th Annual meeting.

3.     Si Nguyen Thu Mai, Huyen Ngoc Vu, Xuan The Hoang, Van Thai Than, Trung Viet Nguyen, Minh Thong Le, Phuc-Loi Luu, Hoa Quynh Tran, Minh Nam Nguyen. Decreased mortality strongly correlated with the upregulation of BCR in breast cancer metastasis to bone. Annals of Oncology. Nov 2018;29, Issue suppl­_9. ESMO Asia 2018 congress.

4.     Nguyen Thuy Vinh, Nguyen Van Bang, Tran Quynh Hoa, Nguyen Thi Hong Hanh Nguyen Thi Loi. A 205 bp-region on HP1125 gene can serve as bio-maker for detecting Helicobacter pylori. The 5^th Congress on Gastroenterology of Southeast Asian Nations. Hanoi, Vietnam 2004:33-35.

5.     Nguyen Thuy Vinh, Hoang Tuan Anh, Tran Quynh Hoa, Le Bang Son, Nguyen Thi Hong Hanh. The sensitivity of the Helicobacter pylori isolated in during the years from 2000 to 2001 to clarithromycin, amoxicillin and metronidazole. Proceedings National Conference on Life Science. 2003:285-288.

6.     Tran Quynh Hoa, Le Bang Son, Nguyen Thi Loi, Hoang Tuan Anh, Nguyen Thi Nguyet, Bui Phuong Thuan, Dang Duc Trach, Nguyen Thi Hong Hanh. The deletion of two nucleotides from the 5’ end of the cagA gene in the genome of Helicobacter pylori, Vietnamese strain. International workshop on Biology. Hanoi, Vietnam 2001;2:198-205.

PRESENTATIONS AND AWARDS

1.     Best presentation award at KSBMB International conference, Jeju, South Korea, 2019. (talk)

2.     Annual Molecular Biology and Biomedicine symposium, Kyung Hee university School of medicine, Seoul, South Korea, 2019. (talk)

3.     KDDW conference, Seoul, South Korea, 2108. (poster)

4.     3^rd prize at Young scientist award, Vietnam academy of science and technology, 2003. (talk)